4EMW
Crystal Structure of Staphylococcus aureus bound with the covalent inhibitor EtVC-CoA
Summary for 4EMW
Entry DOI | 10.2210/pdb4emw/pdb |
Related | 1YQZ 4EM3 4EM4 4EQR 4EQS 4EQW 4EQX |
Descriptor | Coenzyme A disulfide reductase, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Staphylococcus aureus subsp. aureus |
Total number of polymer chains | 2 |
Total formula weight | 101505.01 |
Authors | Edwards, J.S.,Wallace, B.D.,Claiborne, A.,Redinbo, M.R. (deposition date: 2012-04-12, release date: 2012-10-17, Last modification date: 2019-07-17) |
Primary citation | Wallace, B.D.,Edwards, J.S.,Wallen, J.R.,Moolman, W.J.,van der Westhuyzen, R.,Strauss, E.,Redinbo, M.R.,Claiborne, A. Turnover-Dependent Covalent Inactivation of Staphylococcus aureus Coenzyme A-Disulfide Reductase by Coenzyme A-Mimetics: Mechanistic and Structural Insights. Biochemistry, 51:7699-7711, 2012 Cited by PubMed: 22954034DOI: 10.1021/bi301026c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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