4EMU
Crystal structure of ligand free human STING
Summary for 4EMU
Entry DOI | 10.2210/pdb4emu/pdb |
Related | 4EMT |
Descriptor | Transmembrane protein 173, CALCIUM ION (3 entities in total) |
Functional Keywords | alpha/beta fold, innate immune sensor, c-di-gmp, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein : Q86WV6 |
Total number of polymer chains | 2 |
Total formula weight | 43088.39 |
Authors | |
Primary citation | Shu, C.,Yi, G.,Watts, T.,Kao, C.C.,Li, P. Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat.Struct.Mol.Biol., 19:722-724, 2012 Cited by PubMed: 22728658DOI: 10.1038/nsmb.2331 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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