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4EMU

Crystal structure of ligand free human STING

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Transmembrane protein 173polymer18821524.22UniProt (Q86WV6)
Pfam (PF15009)
Homo sapiens (human)Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Stimulator of interferon genes protein, hSTING
2C
(B)
CALCIUM IONnon-polymer40.11Chemie (CA)
3D, E
(A, B)
waterwater18.0146Chemie (HOH)
Sequence modifications
A, B: 155 - 341 (UniProt: Q86WV6)
PDBExternal DatabaseDetails
Ser 154-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43048.3
Non-Polymers*Number of molecules1
Total formula weight40.1
All*Total formula weight43088.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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