4EKY

Crystal structure of GPb in complex with DK15

Summary for 4EKY

• Entry DOI: 10.2210/pdb4eky/pdb
• Related: 4EJ2 4EKE 4EL0 4EL5
• Descriptor: Glycogen phosphorylase, muscle form, 1-(beta-D-glucopyranosyl)-5-(pent-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione (3 entities in total)
• Functional Keywords: alpha/beta protein, transferase
• Biological source: Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits)
• Total number of polymer chains: 1
• Total formula weight: 95849.36

Authors

Kantsadi, A.L.,Skamnaki, V.T.,Leonidas, D.D. (deposition date: 2012-04-10, release date: 2012-07-25, Last modification date: 2023-12-06)

• Primary citation: Kantsadi, A.L.,Manta, S.,Psarra, A.M.,Dimopoulou, A.,Kiritsis, C.,Parmenopoulou, V.,Skamnaki, V.T.,Zoumpoulakis, P.,Zographos, S.E.,Leonidas, D.D.,Komiotis, D.; The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment.; Eur.J.Med.Chem., 54:740-749, 2012; PubMed: 22770609; DOI: 10.1016/j.ejmech.2012.06.029

Experimental method

X-RAY DIFFRACTION (2.45 Å)