4EKK
Akt1 with AMP-PNP
Summary for 4EKK
Entry DOI | 10.2210/pdb4ekk/pdb |
Related | 4EKL |
Descriptor | RAC-alpha serine/threonine-protein kinase, Glycogen synthase kinase-3 beta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total) |
Functional Keywords | phosphotransferase, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P31749 P49841 |
Total number of polymer chains | 4 |
Total formula weight | 82412.52 |
Authors | Wu, W.-I.,Vigers, G.P.A.,Morales, T.H.,Brandhuber, B.J. (deposition date: 2012-04-09, release date: 2012-05-23, Last modification date: 2024-10-09) |
Primary citation | Lin, K.,Lin, J.,Wu, W.I.,Ballard, J.,Lee, B.B.,Gloor, S.L.,Vigers, G.P.,Morales, T.H.,Friedman, L.S.,Skelton, N.,Brandhuber, B.J. An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt. Sci.Signal., 5:ra37-ra37, 2012 Cited by PubMed: 22569334DOI: 10.1126/scisignal.2002618 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report