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4EIY

Crystal structure of the chimeric protein of A2aAR-BRIL in complex with ZM241385 at 1.8A resolution

Summary for 4EIY
Entry DOI10.2210/pdb4eiy/pdb
Related3eml
DescriptorAdenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ... (9 entities in total)
Functional Keywordsnovel protein engineering, gpcr network, psi-biology, structural genomics, membrane protein, gpcr
Biological sourceHomo sapiens (human)
More
Cellular locationCell membrane; Multi-pass membrane protein: P29274
Total number of polymer chains1
Total formula weight58721.97
Authors
Liu, W.,Chun, E.,Thompson, A.A.,Chubukov, P.,Xu, F.,Katritch, V.,Han, G.W.,Heitman, L.H.,Ijzerman, A.P.,Cherezov, V.,Stevens, R.C.,GPCR Network (GPCR) (deposition date: 2012-04-06, release date: 2012-07-25, Last modification date: 2023-09-13)
Primary citationLiu, W.,Chun, E.,Thompson, A.A.,Chubukov, P.,Xu, F.,Katritch, V.,Han, G.W.,Roth, C.B.,Heitman, L.H.,IJzerman, A.P.,Cherezov, V.,Stevens, R.C.
Structural basis for allosteric regulation of GPCRs by sodium ions.
Science, 337:232-236, 2012
Cited by
PubMed: 22798613
DOI: 10.1126/science.1219218
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

數據於2024-03-27公開中

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