4EIG

CA1698 camel antibody fragment in complex with DHFR

Summary for 4EIG

Entry DOI	10.2210/pdb4eig/pdb
Related	4EIZ 4EJ1
Descriptor	Dihydrofolate reductase, CA1698 camel antibody fragment (3 entities in total)
Functional Keywords	nadp binding, oxidoreductase-immune system complex, oxidoreductase/immune system
Biological source	Escherichia coli More
Total number of polymer chains	2
Total formula weight	31644.59
Authors	Oyen, D.,Srinivasan, V. (deposition date: 2012-04-05, release date: 2013-04-24, Last modification date: 2017-11-15)
Primary citation	Oyen, D.,Wechselberger, R.,Srinivasan, V.,Steyaert, J.,Barlow, J.N. Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834:2147-2157, 2013 Cited by PubMed: 23911607 DOI: 10.1016/j.bbapap.2013.07.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation