4EG3
Trypanosoma brucei methionyl-tRNA synthetase in complex with product methionyl-adenylate
Summary for 4EG3
Entry DOI | 10.2210/pdb4eg3/pdb |
Related | 4EG1 4EG4 4EG5 4EG6 4EG7 4EG8 4EGA |
Descriptor | Methionyl-tRNA synthetase, putative, GLYCEROL, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate, ... (4 entities in total) |
Functional Keywords | aminoacyl-trna synthetase, aars, metrs, parasite, ligase, protein-inhibitor complex, rossmann-fold, translation, nucleotide binding, rossmann fold, trna binding atp binding |
Biological source | Trypanosoma brucei brucei |
Total number of polymer chains | 2 |
Total formula weight | 124839.28 |
Authors | Koh, C.Y.,Kim, J.E.,Shibata, S.,Fan, E.,Verlinde, C.L.M.J.,Hol, W.G.J. (deposition date: 2012-03-30, release date: 2012-09-12, Last modification date: 2017-11-15) |
Primary citation | Koh, C.Y.,Kim, J.E.,Shibata, S.,Ranade, R.M.,Yu, M.,Liu, J.,Gillespie, J.R.,Buckner, F.S.,Verlinde, C.L.,Fan, E.,Hol, W.G. Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection. Structure, 20:1681-1691, 2012 Cited by PubMed: 22902861DOI: 10.1016/j.str.2012.07.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.94 Å) |
Structure validation
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