4EG3
Trypanosoma brucei methionyl-tRNA synthetase in complex with product methionyl-adenylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Methionyl-tRNA synthetase, putative | polymer | 542 | 61434.7 | 2 | UniProt (Q38C91) Pfam (PF09334) Pfam (PF19303) | Trypanosoma brucei brucei | |
| 2 | C, D, E, F, G... (A, B) | GLYCEROL | non-polymer | 92.1 | 11 | Chemie (GOL) | |||
| 3 | J, O (A, B) | [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate | non-polymer | 478.4 | 2 | Chemie (ME8) | |||
| 4 | P, Q (A, B) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A, B: 237 - 773 (UniProt: Q38C91)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
| Thr 309 | Ala 309 | conflict |
| Ala 452 | Lys 452 | engineered mutation |
| Arg 453 | Lys 453 | engineered mutation |
| Ala 454 | Glu 454 | engineered mutation |
| Val 499 | Ala 499 | conflict |
| Asn 503 | Ser 503 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 122869.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1969.9 | |
| All* | Total formula weight | 124839.3 |
