4EEE

Crystal Structure of YLDV 14L IL-18 Binding Protein in Complex with Human IL-18

Summary for 4EEE

• Entry DOI: 10.2210/pdb4eee/pdb
• Related: 4EKX
• Descriptor: 14L protein, Interleukin-18 (3 entities in total)
• Functional Keywords: interleukin-18 binding protein, beta trefoil, immunoglobulin fold, yaba, yldv, cytokine signaling, cytokine-viral protein complex, cytokine/viral protein
• Biological source: Yaba-like disease virus (YLDV); More
• Cellular location: Secreted: Q14116
• Total number of polymer chains: 4
• Total formula weight: 63913.04

Authors

Krumm, B.E.,Xiang, Y.,Deng, J. (deposition date: 2012-03-28, release date: 2012-09-26, Last modification date: 2023-09-13)

• Primary citation: Krumm, B.,Meng, X.,Wang, Z.,Xiang, Y.,Deng, J.; A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein.; Plos Pathog., 8:e1002876-e1002876, 2012; PubMed: 22927815; DOI: 10.1371/journal.ppat.1002876

Experimental method

X-RAY DIFFRACTION (2.71 Å)