4EEE
Crystal Structure of YLDV 14L IL-18 Binding Protein in Complex with Human IL-18
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | 14L protein | polymer | 118 | 13997.4 | 2 | UniProt (Q9DHU8) In PDB | Yaba-like disease virus (YLDV) | |
2 | B, D | Interleukin-18 | polymer | 157 | 17959.1 | 2 | UniProt (Q14116) Pfam (PF00340) In PDB | Homo sapiens (human) | IL-18, Iboctadekin, Interferon gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma |
3 | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A, C: 20 - 136 (UniProt: Q9DHU8)
B, D: 1 - 157 (UniProt: Q14116)
PDB | External Database | Details |
---|---|---|
Met 19 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 38 | Cys 74 | engineered mutation |
Ala 67 | Lys 103 | engineered mutation |
Ser 68 | Cys 104 | engineered mutation |
Ala 69 | Glu 105 | engineered mutation |
Ala 70 | Lys 106 | engineered mutation |
Ala 71 | Ile 107 | engineered mutation |
Ser 76 | Cys 112 | engineered mutation |
Ser 127 | Cys 163 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 63913.0 | |
All* | Total formula weight | 63913.0 |