4DZ5
W227F active site mutant of AKR1C3
Summary for 4DZ5
Entry DOI | 10.2210/pdb4dz5/pdb |
Descriptor | Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | tim barrel, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P42330 |
Total number of polymer chains | 1 |
Total formula weight | 39059.15 |
Authors | Squire, C.J.,Yosaatmadja, Y.,Flanagan, J.U. (deposition date: 2012-02-29, release date: 2013-03-06, Last modification date: 2023-09-13) |
Primary citation | Squire, C.J.,Yosaatmadja, Y.,Park, S.,Ko, W.,Guise, C.,Smaill, J.,Patterson, A.,Flanagan, J.U. Validating PR-104A binding to AKR1C3 To be Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report