4DY1

tRNA-guanine transglycosylase F92C C158S C281S mutant

Summary for 4DY1

• Entry DOI: 10.2210/pdb4dy1/pdb
• Related: 1PUD 3HFY 3UNT 3UVI 4DXX
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: functional dimer, protein-protein interface, transferase, guanine exchange enzyme, zinc binding, guanine binding, trna binding
• Biological source: Zymomonas mobilis
• Total number of polymer chains: 1
• Total formula weight: 43159.94

Authors

Jakobi, S.,Heine, A.,Klebe, G. (deposition date: 2012-02-28, release date: 2013-03-27, Last modification date: 2023-09-13)

• Primary citation: Jakobi, S.,Nguyen, P.T.,Debaene, F.,Cianferani, S.,Reuter, K.,Klebe, G.; What Glues a Homodimer Together: Systematic Analysis of the Stabilizing Effect of an Aromatic Hot Spot in the Protein-Protein Interface of the tRNA-Modifying Enzyme Tgt.; Acs Chem.Biol., 10:1897-1907, 2015; PubMed: 25951081; DOI: 10.1021/acschembio.5b00028

Experimental method

X-RAY DIFFRACTION (2.045 Å)