4DVR

Crystal structure of YU2 gp120 core in complex with Fab 48d and NBD-557

4DVR の概要

• エントリーDOI: 10.2210/pdb4dvr/pdb
• 分子名称: Envelope glycoprotein gp120, Fab 48d Light chain, Fab 48d Heavy chain, ... (6 entities in total)
• 機能のキーワード: hiv-1 gp120, cd4 binding site, nbd-557, immune system-transcription inhibitor complex, immune system/transcription inhibitor
• 由来する生物種: Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 83328.08

構造登録者

Kwon, Y.D.,Kwong, P.D. (登録日: 2012-02-23, 公開日: 2013-02-27, 最終更新日: 2023-09-13)

• 主引用文献: Kwon, Y.D.,Lalonde, J.M.,Yang, Y.,Elban, M.A.,Sugawara, A.,Courter, J.R.,Jones, D.M.,Smith, A.B.,Debnath, A.K.,Kwong, P.D.; Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site.; Plos One, 9:e85940-e85940, 2014; PubMed: 24489681; DOI: 10.1371/journal.pone.0085940

実験手法

X-RAY DIFFRACTION (2.5 Å)