4DO8
Crystal structure of the muscarinic toxin MT1
Summary for 4DO8
Entry DOI | 10.2210/pdb4do8/pdb |
Related | 1FF4 2VLW 3FEV 3NEQ |
Descriptor | Muscarinic toxin 1, THIOCYANATE ION, ACETATE ION, ... (4 entities in total) |
Functional Keywords | snake toxin, three-finger toxin fold, muscarinic toxin, muscarinic m1 receptor, neurones, muscarinic m4 receptor, adrenergic receptor, toxin |
Biological source | Dendroaspis angusticeps (Eastern green mamba) |
Cellular location | Secreted: P81030 |
Total number of polymer chains | 2 |
Total formula weight | 15168.37 |
Authors | Fruchart-Gaillard, C.,Mournier, G.,Vera, L.,Servent, D.,Stura, E.A. (deposition date: 2012-02-09, release date: 2012-06-27, Last modification date: 2024-04-03) |
Primary citation | Fruchart-Gaillard, C.,Mourier, G.,Blanchet, G.,Vera, L.,Gilles, N.,Menez, R.,Marcon, E.,Stura, E.A.,Servent, D. Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors. Plos One, 7:e39166-e39166, 2012 Cited by PubMed: 22720062DOI: 10.1371/journal.pone.0039166 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.802 Å) |
Structure validation
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