4DN5
Crystal Structure of NF-kB-inducing Kinase (NIK)
Summary for 4DN5
| Entry DOI | 10.2210/pdb4dn5/pdb |
| Descriptor | Mitogen-activated protein kinase kinase kinase 14, MAGNESIUM ION, GLYCEROL, ... (6 entities in total) |
| Functional Keywords | non-rd kinase, protein serine/threonine kinase, transferase, atp binding |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q99558 |
| Total number of polymer chains | 2 |
| Total formula weight | 79907.04 |
| Authors | Min, X.,Liu, J.,Sudom, A.,Walker, N.P.,Wang, Z. (deposition date: 2012-02-08, release date: 2012-06-27, Last modification date: 2024-02-28) |
| Primary citation | Liu, J.,Sudom, A.,Min, X.,Cao, Z.,Gao, X.,Ayres, M.,Lee, F.,Cao, P.,Johnstone, S.,Plotnikova, O.,Walker, N.,Chen, G.,Wang, Z. Structure of Nuclear Factor Kappa B-inducing kinase domain reveals a constitutively active conformation J.Biol.Chem., 287:27326-27334, 2012 Cited by PubMed: 22718757DOI: 10.1074/jbc.M112.366658 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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