4DMW
Crystal structure of the GT domain of Clostridium difficile toxin A (TcdA) in complex with UDP and Manganese
Summary for 4DMW
| Entry DOI | 10.2210/pdb4dmw/pdb |
| Related | 3SRZ 3SS1 4DMV |
| Descriptor | Toxin A, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... (4 entities in total) |
| Functional Keywords | glucosyltransferase, transferase |
| Biological source | Clostridium difficile |
| Total number of polymer chains | 1 |
| Total formula weight | 65000.77 |
| Authors | Malito, E.,D'Urzo, N.,Bottomley, M.J.,Biancucci, M.,Scarselli, M.,Maione, D.,Martinelli, M. (deposition date: 2012-02-08, release date: 2012-07-18, Last modification date: 2023-09-13) |
| Primary citation | D'Urzo, N.,Malito, E.,Biancucci, M.,Bottomley, M.J.,Maione, D.,Scarselli, M.,Martinelli, M. The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release. Febs J., 279:3085-3097, 2012 Cited by PubMed: 22747490DOI: 10.1111/j.1742-4658.2012.08688.x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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