4DMW

Crystal structure of the GT domain of Clostridium difficile toxin A (TcdA) in complex with UDP and Manganese

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016757	molecular_function	glycosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 601

Chain	Residue
A	ASP287
A	GLU514
A	UDP602
A	HOH763

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE UDP A 602

Chain	Residue
A	TYR283
A	ASP285
A	VAL286
A	ASP287
A	SER517
A	MN601
A	HOH719
A	VAL100
A	TRP101
A	ILE102
A	LEU264
A	SER268

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22267739","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22747490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22267739","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22267739","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SS1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22267739","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22747490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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