4DK9

Crystal Structure of MBD4 Catalytic Domain Bound to Abasic DNA

Summary for 4DK9

• Entry DOI: 10.2210/pdb4dk9/pdb
• Descriptor: 5'-D(*AP*AP*GP*AP*CP*GP*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*T)-3', Methyl-CpG-binding domain protein 4, ... (5 entities in total)
• Functional Keywords: protein-dna complex, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O95243
• Total number of polymer chains: 3
• Total formula weight: 25308.94

Authors

Manvilla, B.A.,Toth, E.A.,Drohat, A.C. (deposition date: 2012-02-03, release date: 2012-04-25, Last modification date: 2024-02-28)

• Primary citation: Manvilla, B.A.,Maiti, A.,Begley, M.C.,Toth, E.A.,Drohat, A.C.; Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA.; J.Mol.Biol., 420:164-175, 2012; PubMed: 22560993; DOI: 10.1016/j.jmb.2012.04.028

Experimental method

X-RAY DIFFRACTION (2.76 Å)