4DK9
Crystal Structure of MBD4 Catalytic Domain Bound to Abasic DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 5'-D(*AP*AP*GP*AP*CP*GP*TP*GP*GP*AP*C)-3' | polymer | 11 | 3407.2 | 1 | |||
| 2 | B (C) | 5'-D(*TP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*T)-3' | polymer | 11 | 3191.1 | 1 | |||
| 3 | C (A) | Methyl-CpG-binding domain protein 4 | polymer | 157 | 18671.5 | 1 | UniProt (O95243) | Homo sapiens (human) | Methyl-CpG-binding endonuclease 1, Methyl-CpG-binding protein MBD4, Mismatch-specific DNA N-glycosylase |
| 4 | D (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 5 | E (B) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 426 - 580 (UniProt: O95243)
| PDB | External Database | Details |
|---|---|---|
| Gly 424 | - | expression tag |
| Ser 425 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 25269.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 39.1 | |
| All* | Total formula weight | 25308.9 |
