4DE4
Crystal structure of aminoglycoside phosphotransferase APH(2")-Id/APH(2")-IVa in complex with HEPES
Replaces: 3R80Summary for 4DE4
Entry DOI | 10.2210/pdb4de4/pdb |
Related | 3R7Z 3R81 3R82 |
Descriptor | APH(2")-Id, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total) |
Functional Keywords | structural genomics, center for structural genomics of infectious diseases, csgid, niaid, national institute of allergy and infectious diseases, eukaryotic protein kinase-like fold, aminoglycoside phosphotransferase, kinase, transferase, aminoglycosides, intracellular |
Biological source | Enterococcus casseliflavus |
Total number of polymer chains | 2 |
Total formula weight | 77034.69 |
Authors | Stogios, P.J.,Minasov, G.,Tan, K.,Nocek, B.,Evdokimova, E.,Egorova, O.,Di Leo, R.,Li, H.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-01-19, release date: 2012-02-08, Last modification date: 2018-01-24) |
Primary citation | Shakya, T.,Stogios, P.J.,Waglechner, N.,Evdokimova, E.,Ejim, L.,Blanchard, J.E.,McArthur, A.G.,Savchenko, A.,Wright, G.D. A small molecule discrimination map of the antibiotic resistance kinome. Chem.Biol., 18:1591-1601, 2011 Cited by PubMed: 22195561DOI: 10.1016/j.chembiol.2011.10.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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