4DDI
Crystal structure of human OTUB1/UbcH5b~Ub/Ub
Summary for 4DDI
Entry DOI | 10.2210/pdb4ddi/pdb |
Related | 4DDG |
Descriptor | Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1, Polyubiquitin-C (2 entities in total) |
Functional Keywords | hydrolase-ligase complex, inhibition, hydrolase/ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : Q96FW1 Ubiquitin: Cytoplasm : P0CG48 |
Total number of polymer chains | 9 |
Total formula weight | 188808.61 |
Authors | Juang, Y.C.,Sanches, M.,Sicheri, F. (deposition date: 2012-01-18, release date: 2012-02-22, Last modification date: 2017-11-15) |
Primary citation | Juang, Y.C.,Landry, M.C.,Sanches, M.,Vittal, V.,Leung, C.C.,Ceccarelli, D.F.,Mateo, A.R.,Pruneda, J.N.,Mao, D.Y.,Szilard, R.K.,Orlicky, S.,Munro, M.,Brzovic, P.S.,Klevit, R.E.,Sicheri, F.,Durocher, D. OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function. Mol.Cell, 45:384-397, 2012 Cited by PubMed: 22325355DOI: 10.1016/j.molcel.2012.01.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.802 Å) |
Structure validation
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