4DA4
Structure of mouse DNMT1 (731-1602) bound to hemimethylated CpG DNA
Summary for 4DA4
Entry DOI | 10.2210/pdb4da4/pdb |
Descriptor | DNA (cytosine-5)-methyltransferase 1, DNA_UPPER_STRAND, DNA_LOWER_STRAND, ... (7 entities in total) |
Functional Keywords | maintenance dna methylation, covalent complex, transferase-dna complex, transferase/dna |
Biological source | Mus musculus (mouse) More |
Cellular location | Nucleus: P13864 |
Total number of polymer chains | 6 |
Total formula weight | 213997.43 |
Authors | Song, J.,Patel, D.J. (deposition date: 2012-01-12, release date: 2012-02-22, Last modification date: 2024-02-28) |
Primary citation | Song, J.,Teplova, M.,Ishibe-Murakami, S.,Patel, D.J. Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation. Science, 335:709-712, 2012 Cited by PubMed: 22323818DOI: 10.1126/science.1214453 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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