4DA4
Structure of mouse DNMT1 (731-1602) bound to hemimethylated CpG DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA (cytosine-5)-methyltransferase 1 | polymer | 873 | 98980.6 | 2 | UniProt (P13864) Pfam (PF01426) Pfam (PF00145) | Mus musculus (mouse) | Dnmt1, Met-1, DNA methyltransferase MmuI, DNA MTase MmuI, M.MmuI, MCMT |
| 2 | C, E (C, E) | DNA_UPPER_STRAND | polymer | 12 | 3678.4 | 2 | |||
| 3 | D, F (D, F) | DNA_LOWER_STRAND | polymer | 12 | 3728.5 | 2 | |||
| 4 | G, J (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 5 | H, I, K, L (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 6 | M (B) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 7 | N, O, P, Q, R... (A, B, C, D, E...) | water | water | 18.0 | 860 | Chemie (HOH) |
Sequence modifications
A, B: 731 - 1602 (UniProt: P13864)
| PDB | External Database | Details |
|---|---|---|
| Ser 730 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 212774.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1222.6 | |
| All* | Total formula weight | 213997.4 |
