4D86

Human PARP14 (ARTD8, BAL2) - macro domains 1 and 2 in complex with adenosine-5-diphosphate

Summary for 4D86

• Entry DOI: 10.2210/pdb4d86/pdb
• Related: 3VFQ
• Descriptor: Poly [ADP-ribose] polymerase 14, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: transferase, adp-ribose, parp14, macro, bal2, artd8, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q460N5
• Total number of polymer chains: 1
• Total formula weight: 45561.82

Authors

Karlberg, T.,Thorsell, A.G.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Ekblad, T.,Weigelt, J.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2012-01-10, release date: 2013-03-13, Last modification date: 2023-09-13)

• Primary citation: Forst, A.H.,Karlberg, T.,Herzog, N.,Thorsell, A.G.,Gross, A.,Feijs, K.L.,Verheugd, P.,Kursula, P.,Nijmeijer, B.,Kremmer, E.,Kleine, H.,Ladurner, A.G.,Schuler, H.,Luscher, B.; Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains.; Structure, 21:462-475, 2013; PubMed: 23473667; DOI: 10.1016/j.str.2012.12.019

Experimental method

X-RAY DIFFRACTION (2 Å)