4D86
Human PARP14 (ARTD8, BAL2) - macro domains 1 and 2 in complex with adenosine-5-diphosphate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADP A 1201 |
| Chain | Residue |
| A | ALA822 |
| A | VAL962 |
| A | HOH1307 |
| A | HOH1352 |
| A | HOH1375 |
| A | GLY832 |
| A | LEU833 |
| A | SER922 |
| A | SER923 |
| A | GLY924 |
| A | VAL925 |
| A | PHE926 |
| A | ASP961 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP A 1202 |
| Chain | Residue |
| A | GLY1022 |
| A | VAL1023 |
| A | GLN1024 |
| A | SER1034 |
| A | PRO1045 |
| A | LEU1046 |
| A | SER1049 |
| A | ALA1131 |
| A | GLY1133 |
| A | THR1134 |
| A | GLY1135 |
| A | ASN1136 |
| A | LEU1137 |
| A | HIS1172 |
| A | ASP1175 |
| A | ASN1178 |
| A | HOH1323 |
| A | HOH1339 |
| A | HOH1358 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 187 |
| Details | Domain: {"description":"Macro 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00490","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23473667","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q6Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23473667","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VFQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23473667","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ABK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
