4D86
Human PARP14 (ARTD8, BAL2) - macro domains 1 and 2 in complex with adenosine-5-diphosphate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADP A 1201 |
| Chain | Residue |
| A | ALA822 |
| A | VAL962 |
| A | HOH1307 |
| A | HOH1352 |
| A | HOH1375 |
| A | GLY832 |
| A | LEU833 |
| A | SER922 |
| A | SER923 |
| A | GLY924 |
| A | VAL925 |
| A | PHE926 |
| A | ASP961 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP A 1202 |
| Chain | Residue |
| A | GLY1022 |
| A | VAL1023 |
| A | GLN1024 |
| A | SER1034 |
| A | PRO1045 |
| A | LEU1046 |
| A | SER1049 |
| A | ALA1131 |
| A | GLY1133 |
| A | THR1134 |
| A | GLY1135 |
| A | ASN1136 |
| A | LEU1137 |
| A | HIS1172 |
| A | ASP1175 |
| A | ASN1178 |
| A | HOH1323 |
| A | HOH1339 |
| A | HOH1358 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23473667, ECO:0007744|PDB:3Q6Z |
| Chain | Residue | Details |
| A | ASN824 | |
| A | LEU833 | |
| A | SER922 | |
| A | ASP961 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23473667, ECO:0007744|PDB:3Q71, ECO:0007744|PDB:3VFQ |
| Chain | Residue | Details |
| A | VAL1023 | |
| A | LEU1046 | |
| A | GLY1133 | |
| A | ASP1175 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23473667, ECO:0007744|PDB:4ABK |
| Chain | Residue | Details |
| A | SER1034 |
