4D5L

Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state

Summary for 4D5L

Related4D5N 4D5Y 4D61 4D66 4D67 4D68
EMDB information2810
Descriptor18S RRNA 2, 40S RIBOSOMAL PROTEIN ES26, 40S RIBOSOMAL PROTEIN ES27, ... (34 entities in total)
Functional Keywordscrpv ires, ribosome, termination, release factors
Biological sourceORYCTOLAGUS CUNICULUS (RABBIT)
Cellular locationCytoplasm  G1SS70
Total number of polymer chains34
Total molecular weight1221711.59
Authors
Muhs, M.,Hilal, T.,Mielke, T.,Skabkin, M.A.,Sanbonmatsu, K.Y.,Pestova, T.V.,Spahn, C.M.T. (deposition date: 2014-11-05, release date: 2015-02-04, Last modification date: 2017-08-23)
Primary citation
Muhs, M.,Hilal, T.,Mielke, T.,Skabkin, M.A.,Sanbonmatsu, K.Y.,Pestova, T.V.,Spahn, C.M.T.
Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57:422-, 2015
PubMed: 25601755 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2014.12.016
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (9 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone413.1%4.7%0.20MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures