4D3U

Structure of Bacillus subtilis Nitric Oxide Synthase H128S in complex with N-{3-[(1S)-2-(3-{(Z)-[amino(thiophen-2-yl)methylidene]amino}phenoxy)-1-hydroxyethyl]phenyl}thiophene-2-carboximidamide

Summary for 4D3U

Entry DOI	10.2210/pdb4d3u/pdb
Related	4D3I 4D3J 4D3K 4D3M 4D3N 4D3O 4D3T 4D3V
Descriptor	NITRIC OXIDE SYNTHASE OXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	oxidoreductase, inhibitor
Biological source	BACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168
Total number of polymer chains	1
Total formula weight	43496.29
Authors	Holden, J.K.,Poulos, T.L. (deposition date: 2014-10-23, release date: 2015-01-14, Last modification date: 2023-12-20)
Primary citation	Holden, J.K.,Kang, S.,Hollingsworth, S.A.,Li, H.,Lim, N.,Chen, S.,Huang, H.,Xue, F.,Tang, W.,Silverman, R.B.,Poulos, T.L. Structure-Based Design of Bacterial Nitric Oxide Synthase Inhibitors. J.Med.Chem., 58:994-, 2015 Cited by PubMed: 25522110 DOI: 10.1021/JM501723P PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.981 Å)

Structure validation