4CXT
BTB domain of KEAP1 in complex with CDDO
Summary for 4CXT
Entry DOI | 10.2210/pdb4cxt/pdb |
Related | 4CXI 4CXJ |
Descriptor | KELCH-LIKE ECH-ASSOCIATED PROTEIN 1, (13alpha,18alpha)-2-cyano-3-hydroxy-12-oxooleana-2,9(11)-dien-28-oic acid (3 entities in total) |
Functional Keywords | signaling protein, btb domain, keap1 |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: Q14145 |
Total number of polymer chains | 1 |
Total formula weight | 15787.33 |
Authors | Cleasby, A.,Yon, J.,Day, P.J.,Richardson, C.,Tickle, I.J.,Williams, P.A.,Callahan, J.F.,Carr, R.,Concha, N.,Kerns, J.K.,Qi, H.,Sweitzer, T.,Ward, P.,Davies, T.G. (deposition date: 2014-04-08, release date: 2014-06-18) |
Primary citation | Cleasby, A.,Yon, J.,Day, P.J.,Richardson, C.,Tickle, I.J.,Williams, P.A.,Callahan, J.F.,Carr, R.,Concha, N.,Kerns, J.K.,Qi, H.,Sweitzer, T.,Ward, P.,Davies, T.G. Structure of the Btb Domain of Keap1 and its Interaction with the Triterpenoid Antagonist Cddo. Plos One, 9:98896-, 2014 Cited by PubMed: 24896564DOI: 10.1371/JOURNAL.PONE.0098896 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
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