4CXT
BTB domain of KEAP1 in complex with CDDO
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 | polymer | 137 | 15293.7 | 1 | UniProt (Q14145) Pfam (PF00651) In PDB | HOMO SAPIENS (HUMAN) | CYTOSOLIC INHIBITOR OF NRF2, INRF2, KELCH-LIKE PROTEIN 19, KEAP1 |
| 2 | A | (13alpha,18alpha)-2-cyano-3-hydroxy-12-oxooleana-2,9(11)-dien-28-oic acid | non-polymer | 493.7 | 1 | Chemie (SXJ) | |||
| 3 | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A: 48 - 180 (UniProt: Q14145)
| PDB | External Database | Details |
|---|---|---|
| Gly 44 | - | expression tag |
| Ser 45 | - | expression tag |
| His 46 | - | expression tag |
| Met 47 | - | expression tag |
| Ala 172 | Ser 172 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15293.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 493.7 | |
| All* | Total formula weight | 15787.3 |
