4CR8

Crystal structure of the N-acetyl-D-mannosamine dehydrogenase with NAD

Summary for 4CR8

• Entry DOI: 10.2210/pdb4cr8/pdb
• Related: 4CR6 4CR7
• Descriptor: N-ACYLMANNOSAMINE 1-DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• Functional Keywords: oxidoreductase, short-chain dehydrogenase/reductase, substrate selectivity
• Biological source: FLAVOBACTERIUM SP. 141-8
• Total number of polymer chains: 8
• Total formula weight: 225270.17

Authors

Gil-Ortiz, F.,Sola-Carvajal, A.,Garcia-Carmona, F.,Sanchez-Ferrer, A.,Rubio, V. (deposition date: 2014-02-25, release date: 2014-07-09, Last modification date: 2023-12-20)

• Primary citation: Sola-Carvajal, A.,Gil-Ortiz, F.,Garcia-Carmona, F.,Rubio, V.,Sanchez-Ferrer, A.; Crystal Structures and Functional Studies Clarify Substrate Selectivity and Catalytic Residues for the Unique Orphan Enzyme N-Acetyl-D-Mannosamine Dehydrogenase.; Biochem.J., 462:499-, 2014; PubMed: 24969681; DOI: 10.1042/BJ20140266

Experimental method

X-RAY DIFFRACTION (2.2 Å)