4CMN

Crystal structure of OCRL in complex with a phosphate ion

Summary for 4CMN

• Entry DOI: 10.2210/pdb4cmn/pdb
• Related: 4CML
• Descriptor: INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL-1, PHOSPHATE ION, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: hydrolase, inositol signalling, sgc stockholm, structural genomics consortium, lowe syndrome, dent disease
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasmic vesicle, phagosome membrane (By similarity): Q01968
• Total number of polymer chains: 1
• Total formula weight: 41845.08

Authors

Tresaugues, L.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Edwards, A.M.,Ekblad, T.,Flodin, S.,Graslund, S.,Karlberg, T.,Nyman, T.,Schuler, H.,Silvander, C.,Thorsell, A.G.,Weigelt, J.,Welin, M.,Nordlund, P. (deposition date: 2014-01-16, release date: 2014-04-16, Last modification date: 2023-12-20)

• Primary citation: Tresaugues, L.,Silvander, C.,Flodin, S.,Welin, M.,Nyman, T.,Graslund, S.,Hammarstrom, M.,Berglund, H.,Nordlund, P.; Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases.; Structure, 22:744-, 2014; PubMed: 24704254; DOI: 10.1016/J.STR.2014.01.013

Experimental method

X-RAY DIFFRACTION (3.13 Å)