4CMN
Crystal structure of OCRL in complex with a phosphate ion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL-1 | polymer | 354 | 41541.6 | 1 | UniProt (Q01968) Pfam (PF03372) | HOMO SAPIENS (HUMAN) | LOWE OCULOCEREBRORENAL SYNDROME PROTEIN, INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL-1 ISOFORM 1 |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F (A) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 215 - 560 (UniProt: Q01968)
| PDB | External Database | Details |
|---|---|---|
| Met 214 | - | expression tag |
| Ala 561 | - | expression tag |
| His 562 | - | expression tag |
| His 563 | - | expression tag |
| His 564 | - | expression tag |
| His 565 | - | expression tag |
| His 566 | - | expression tag |
| His 567 | - | expression tag |
| Gly 428 | Cys 428 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41541.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 303.5 | |
| All* | Total formula weight | 41845.1 |
