4CML
Crystal Structure of INPP5B in complex with Phosphatidylinositol 3,4- bisphosphate
Summary for 4CML
Entry DOI | 10.2210/pdb4cml/pdb |
Related | 4CMN |
Descriptor | TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5- PHOSPHATASE, ISOFORM 2, 1,2-dioctanoyl phosphatidyl epi-inositol (3,4)-bisphosphate, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | hydrolase, sgc, signalling, structural genomics consortium stockholm, magnesium binding |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm, cytosol : P32019 |
Total number of polymer chains | 1 |
Total formula weight | 37195.57 |
Authors | Tresaugues, L.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Edwards, A.M.,Ekblad, T.,Flodin, S.,Graslund, S.,Karlberg, T.,Moche, M.,Nyman, T.,Schuler, H.,Silvander, C.,Thorsell, A.G.,Weigelt, J.,Welin, M.,Nordlund, P. (deposition date: 2014-01-16, release date: 2014-04-16, Last modification date: 2023-12-20) |
Primary citation | Tresaugues, L.,Silvander, C.,Flodin, S.,Welin, M.,Nyman, T.,Graslund, S.,Hammarstrom, M.,Berglund, H.,Nordlund, P. Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases. Structure, 22:744-, 2014 Cited by PubMed: 24704254DOI: 10.1016/J.STR.2014.01.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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