4CML
Crystal Structure of INPP5B in complex with Phosphatidylinositol 3,4- bisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5- PHOSPHATASE, ISOFORM 2 | polymer | 313 | 36201.1 | 1 | UniProt (P32019) Pfam (PF22669) | HOMO SAPIENS (HUMAN) | 75 KDA INOSITOL POLYPHOSPHATE-5-PHOSPHATASE, PHOSPHOINOSITIDE 5-PHOSPHATASE, 5PTASE |
| 2 | B (A) | 1,2-dioctanoyl phosphatidyl epi-inositol (3,4)-bisphosphate | non-polymer | 746.6 | 1 | Chemie (52N) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | G (A) | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence modifications
A: 259 - 563 (UniProt: P32019)
| PDB | External Database | Details |
|---|---|---|
| Met 258 | - | expression tag |
| Ala 564 | - | expression tag |
| His 565 | - | expression tag |
| His 566 | - | expression tag |
| His 567 | - | expression tag |
| His 568 | - | expression tag |
| His 569 | - | expression tag |
| His 570 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36201.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 994.5 | |
| All* | Total formula weight | 37195.6 |
