4CLK

Crystal structure of human soluble Adenylyl Cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate

Summary for 4CLK

Entry DOI	10.2210/pdb4clk/pdb
Related	4CLF 4CLL 4CLP 4CLS 4CLT 4CLU 4CLW 4CLY 4CLZ 4CM0 4CM2
Descriptor	ADENYLATE CYCLASE TYPE 10, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	lyase, adenosine-3'\, 5'-cyclic-monophosphate, adenosine-5'-triphosphate
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	55158.73
Authors	Kleinboelting, S.,Weyand, M.,Steegborn, C. (deposition date: 2014-01-15, release date: 2014-03-05, Last modification date: 2023-12-20)
Primary citation	Kleinboelting, S.,Diaz, A.,Moniot, S.,Van Den Heuvel, J.,Weyand, M.,Levin, L.R.,Buck, J.,Steegborn, C. Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate. Proc.Natl.Acad.Sci.USA, 111:3727-, 2014 Cited by PubMed: 24567411 DOI: 10.1073/PNAS.1322778111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation