4CIN
Complex of Bcl-xL with its BH3 domain
Summary for 4CIN
Entry DOI | 10.2210/pdb4cin/pdb |
Related | 4CIM |
Descriptor | BCL-2-LIKE PROTEIN 1, CALCIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (6 entities in total) |
Functional Keywords | apoptosis |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817 Q07817 |
Total number of polymer chains | 4 |
Total formula weight | 42357.50 |
Authors | Colman, P.M.,Lee, E.F.,Fairlie, W.D. (deposition date: 2013-12-12, release date: 2014-11-12, Last modification date: 2023-12-20) |
Primary citation | Lee, E.F.,Dewson, G.,Evangelista, M.,Pettikiriarachchi, A.,Zhu, H.,Colman, P.M.,Fairlie, W.D. The Functional Differences of Pro-Survival and Pro-Apoptotic B Cell Lymphoma 2 (Bcl-2) Proteins Depend on Structural Differences in Their Bcl-2 Homology 3 (Bh3) Domains J.Biol.Chem., 289:36001-, 2014 Cited by PubMed: 25371206DOI: 10.1074/JBC.M114.610758 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.693 Å) |
Structure validation
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