Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
| C | 0042981 | biological_process | regulation of apoptotic process |
| D | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 1198 |
| Chain | Residue |
| A | SER2 |
| A | GLU124 |
| B | ASN175 |
| B | GLU179 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 1198 |
| Chain | Residue |
| A | ASP176 |
| B | GLY186 |
| B | ASP189 |
| B | EDO1203 |
| B | HOH2021 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE EPE B 1199 |
| Chain | Residue |
| A | GLU7 |
| A | ASP11 |
| A | ARG91 |
| B | VAL10 |
| B | ASP11 |
| B | SER14 |
| B | SER18 |
| B | TRP24 |
| B | SER25 |
| B | MET83 |
| B | ALA84 |
| B | LYS87 |
| B | GLN88 |
| B | ARG91 |
| B | HOH2008 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE EPE A 1199 |
| Chain | Residue |
| A | VAL10 |
| A | ASP11 |
| A | SER14 |
| A | SER18 |
| A | SER25 |
| A | MET83 |
| A | ALA84 |
| A | LYS87 |
| A | GLN88 |
| A | ARG91 |
| B | GLU7 |
| B | ASP11 |
| B | ARG91 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 1200 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 1201 |
| Chain | Residue |
| A | VAL163 |
| B | TRP24 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1200 |
| Chain | Residue |
| A | VAL155 |
| A | GLU158 |
| A | GLN160 |
| A | HOH2036 |
| B | TYR22 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1202 |
| Chain | Residue |
| B | VAL86 |
| B | HOH2009 |
| B | HOH2022 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1201 |
| Chain | Residue |
| A | TYR120 |
| A | ASN128 |
| B | GLU179 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1203 |
| Chain | Residue |
| A | ASP176 |
| B | ASP189 |
| B | GLU193 |
| B | CA1198 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 19 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG |
| Chain | Residue | Details |
| A | LEU130-GLY148 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV |
| Chain | Residue | Details |
| A | TRP181-VAL192 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR |
| Chain | Residue | Details |
| C | VAL8-ARG22 | |
| A | VAL86-ARG100 | |
| site_id | PS01260 |
| Number of Residues | 21 |
| Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW |
| Chain | Residue | Details |
| A | SER4-TRP24 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by caspase-1 |
| Chain | Residue | Details |
| A | GLY117 | |
| B | GLY117 | |
| Chain | Residue | Details |
| A | PHE105 | |
| B | PHE105 | |
| Chain | Residue | Details |
| A | THR118 | |
| B | THR118 | |
