4CGY
Crystal structure of the human topoisomerase III alpha-RMI1 complex
Summary for 4CGY
Entry DOI | 10.2210/pdb4cgy/pdb |
Descriptor | DNA TOPOISOMERASE 3-ALPHA, RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | dna replication-isomerase complex, double holliday junction dissolution, decatenation, minimal dissolvasome, dna replication/isomerase |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 111253.40 |
Authors | Bocquet, N.,Bunker, R.D.,Thoma, N.H. (deposition date: 2013-11-27, release date: 2014-02-12, Last modification date: 2023-12-20) |
Primary citation | Bocquet, N.,Bizard, A.H.,Abdulrahman, W.,Larsen, N.B.,Faty, M.,Cavadini, S.,Bunker, R.D.,Kowalczykowski, S.C.,Cejka, P.,Hickson, I.D.,Thoma, N.H. Structural and Mechanistic Insight Into Holliday-Junction Dissolution by Topoisomerase Iiialpha and Rmi1 Nat.Struct.Mol.Biol., 21:261-, 2014 Cited by PubMed: 24509834DOI: 10.1038/NSMB.2775 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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