4CG7

Cryo-EM of the Sec61-complex bound to the idle 80S ribosome

Summary for 4CG7

Related4CG5 4CG6
EMDB information2510
DescriptorPROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA, TRANSPORT PROTEIN SEC61 SUBUNIT BETA (3 entities in total)
Functional Keywordsprotein transport, co-translational protein translocation
Biological sourceCANIS LUPUS FAMILIARIS (DOG)
Cellular locationEndoplasmic reticulum membrane ; Multi-pass membrane protein  P38377
Endoplasmic reticulum membrane; Single-pass membrane protein P60058
Total number of polymer chains3
Total molecular weight64024.5
Authors
Gogala, M.,Becker, T.,Beatrix, B.,Barrio-Garcia, C.,Berninghausen, O.,Beckmann, R. (deposition date: 2013-11-21, release date: 2014-02-05, Last modification date: 2017-08-30)
Primary citation
Gogala, M.,Becker, T.,Beatrix, B.,Armache, J.,Barrio-Garcia, C.,Berninghausen, O.,Beckmann, R.
Structures of the Sec61 Complex Engaged in Nascent Peptide Translocation or Membrane Insertion.
Nature, 506:107-, 2014
PubMed: 24499919 (PDB entries with the same primary citation)
DOI: 10.1038/NATURE12950
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (6.9 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers611.2%16.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures