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4CFE

Structure of full length human AMPK in complex with a small molecule activator, a benzimidazole derivative (991)

Summary for 4CFE
Entry DOI10.2210/pdb4cfe/pdb
Descriptor5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ... (7 entities in total)
Functional Keywordstransferase, nucleotide-binding, staurosporine-binding, serine/threonine-protein kinase, activator, carbohydrate binding module (cbm)
Biological sourceHOMO SAPIENS (HUMAN)
More
Total number of polymer chains6
Total formula weight273331.57
Authors
Primary citationXiao, B.,Sanders, M.J.,Carmena, D.,Bright, N.J.,Haire, L.F.,Underwood, E.,Patel, B.R.,Heath, R.B.,Walker, P.A.,Hallen, S.,Giordanetto, F.,Martin, S.R.,Carling, D.,Gamblin, S.J.
Structural Basis of Ampk Regulation by Small Molecule Activators.
Nat.Commun., 4:3017-, 2013
Cited by
PubMed: 24352254
DOI: 10.1038/NCOMMS4017
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.023 Å)
Structure validation

217157

건을2024-03-13부터공개중

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