4CDK

Structure of ZNRF3-RSPO1

Summary for 4CDK

• Entry DOI: 10.2210/pdb4cdk/pdb
• Related: 4CDJ
• Descriptor: E3 UBIQUITIN-PROTEIN LIGASE ZNRF3, R-SPONDIN-1 (3 entities in total)
• Functional Keywords: ligase, wnt signaling, adult stem cells, e3 ligase, protease-associated domain, zinc ring finger, lgr5, r-spondin
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Total number of polymer chains: 8
• Total formula weight: 126772.38

Authors

Peng, W.C.,de Lau, W.,Madoori, P.K.,Forneris, F.,Granneman, J.C.M.,Clevers, H.,Gros, P. (deposition date: 2013-11-01, release date: 2014-01-08, Last modification date: 2019-04-03)

• Primary citation: Peng, W.C.,De Lau, W.,Madoori, P.K.,Forneris, F.,Granneman, J.C.M.,Clevers, H.,Gros, P.; Structures of Wnt-Antagonist Znrf3 and its Complex with R-Spondin 1 and Implications for Signaling.; Plos One, 8:83110-, 2013; PubMed: 24349440; DOI: 10.1371/JOURNAL.PONE.0083110

Experimental method

X-RAY DIFFRACTION (2.8 Å)