4CDK
Structure of ZNRF3-RSPO1
Summary for 4CDK
Entry DOI | 10.2210/pdb4cdk/pdb |
Related | 4CDJ |
Descriptor | E3 UBIQUITIN-PROTEIN LIGASE ZNRF3, R-SPONDIN-1 (3 entities in total) |
Functional Keywords | ligase, wnt signaling, adult stem cells, e3 ligase, protease-associated domain, zinc ring finger, lgr5, r-spondin |
Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
Total number of polymer chains | 8 |
Total formula weight | 126772.38 |
Authors | Peng, W.C.,de Lau, W.,Madoori, P.K.,Forneris, F.,Granneman, J.C.M.,Clevers, H.,Gros, P. (deposition date: 2013-11-01, release date: 2014-01-08, Last modification date: 2019-04-03) |
Primary citation | Peng, W.C.,De Lau, W.,Madoori, P.K.,Forneris, F.,Granneman, J.C.M.,Clevers, H.,Gros, P. Structures of Wnt-Antagonist Znrf3 and its Complex with R-Spondin 1 and Implications for Signaling. Plos One, 8:83110-, 2013 Cited by PubMed: 24349440DOI: 10.1371/JOURNAL.PONE.0083110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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