4CDK

Structure of ZNRF3-RSPO1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	E3 UBIQUITIN-PROTEIN LIGASE ZNRF3	polymer	164	17986.3	4	UniProt (Q5SSZ7) Pfam (PF18212) In PDB	MUS MUSCULUS (HOUSE MOUSE)	ZINC/RING FINGER PROTEIN 3
2	E, F, G, H	R-SPONDIN-1	polymer	126	13706.8	4	UniProt (Q2MKA7) Pfam (PF15913) In PDB	HOMO SAPIENS (HHUMA)	ROOF PLATE-SPECIFIC SPONDIN-1, HRSPO1, R-SPONDIN 1
3		water	water		18.0	55	Chemie (HOH)

Sequence modifications

A, B, C, D: 56 - 208 (UniProt: Q5SSZ7)

PDB	External Database	Details
Gly 54	-	expression tag
Ser 55	-	expression tag
Ala 209	-	expression tag
Ala 210	-	expression tag
Ala 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag

E, F, G, H: 31 - 145 (UniProt: Q2MKA7)

PDB	External Database	Details
Gly 29	-	expression tag
Ser 30	-	expression tag
Ala 146	-	expression tag
Ala 147	-	expression tag
Ala 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	126772.4
All*	Total formula weight	126772.4

*Water molecules are not included.