4CD3

RnNTPDase2 X4 variant in complex with PSB-071

Summary for 4CD3

Entry DOI	10.2210/pdb4cd3/pdb
Related	4CD1
Descriptor	ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2, 1-AMINO-4-(3-METHYLPHENYL)AMINO-9,10-DIOXO-9,10-DIHYDROANTHRACENE-2-SULFONATE, GLYCEROL, ... (4 entities in total)
Functional Keywords	hydrolase, apyrase, atpase, purinergic signalling, drug design, inhibitor, ntpdase
Biological source	RATTUS NORVEGICUS (NORWAY RAT)
Cellular location	Isoform 1: Cell membrane; Multi-pass membrane protein (By similarity): O35795
Total number of polymer chains	1
Total formula weight	51493.87
Authors	Zebisch, M.,Schaefer, P.,Straeter, N. (deposition date: 2013-10-29, release date: 2014-02-12, Last modification date: 2014-03-12)
Primary citation	Zebisch, M.,Baqi, Y.,Schafer, P.,Muller, C.E.,Strater, N. Crystal Structure of Ntpdase2 in Complex with the Sulfoanthraquinone Inhibitor Psb-071. J.Struct.Biol., 185:336-, 2014 Cited by PubMed: 24462745 DOI: 10.1016/J.JSB.2014.01.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation