4CD3

RnNTPDase2 X4 variant in complex with PSB-071

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 8E9 A 1462

Chain	Residue
A	HIS50
A	ARG245
A	ASP246
A	LEU249
A	LYS392
A	THR393
A	ARG394
A	TYR398
A	8E91463

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 8E9 A 1463

Chain	Residue
A	HIS50
A	ASP76
A	ARG245
A	SER346
A	ALA347
A	TYR350
A	TYR398
A	8E91462
A	HOH2024

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1464

Chain	Residue
A	TRP185
A	LEU226
A	ASN443
A	HOH2193
A	HOH2195

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Functional Information from PROSITE/UniProt

site_id	PS01238
Number of Residues	16
Details	GDA1_CD39_NTPASE GDA1/CD39 family of nucleoside phosphatases signature. LsGqdEGvFgWVTaNY

Chain	Residue	Details
A	LEU160-TYR175

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"18458329","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18458329","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"24090084","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	5
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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