4CAV

Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a benzofuran ligand R0-09-4879

Summary for 4CAV

Entry DOI	10.2210/pdb4cav/pdb
Related	4CAW 4CAX
Descriptor	GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, CHLORIDE ION, 3-[[3-methyl-2-[[2,3,4-tris(fluoranyl)phenoxy]methyl]-1-benzofuran-4-yl]oxy]-N-(pyridin-3-ylmethyl)propan-1-amine, ... (5 entities in total)
Functional Keywords	transferase, drug discovery
Biological source	ASPERGILLUS FUMIGATUS
Cellular location	Cytoplasm: Q9UVX3
Total number of polymer chains	1
Total formula weight	48913.05
Authors	Robinson, D.A.,Fang, W.,Raimi, O.G.,Blair, D.E.,Harrison, J.,Ruda, G.F.,Lockhart, D.E.A.,Torrie, L.S.,Wyatt, P.G.,Gilbert, I.H.,Van Aalten, D.M.F. (deposition date: 2013-10-09, release date: 2014-09-17, Last modification date: 2023-12-20)
Primary citation	Fang, W.,Robinson, D.A.,Raimi, O.G.,Blair, D.E.,Harrison, J.R.,Lockhart, D.E.A.,Torrie, L.S.,Ruda, G.F.,Wyatt, P.G.,Gilbert, I.H.,Van Aalten, D.M.F. N-Myristoyltransferase is a Cell Wall Target in Aspergillus Fumigatus. Acs Chem.Biol., 10:1425-, 2015 Cited by PubMed: 25706802 DOI: 10.1021/CB5008647 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation