4CAV
Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a benzofuran ligand R0-09-4879
Summary for 4CAV
Entry DOI | 10.2210/pdb4cav/pdb |
Related | 4CAW 4CAX |
Descriptor | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, CHLORIDE ION, 3-[[3-methyl-2-[[2,3,4-tris(fluoranyl)phenoxy]methyl]-1-benzofuran-4-yl]oxy]-N-(pyridin-3-ylmethyl)propan-1-amine, ... (5 entities in total) |
Functional Keywords | transferase, drug discovery |
Biological source | ASPERGILLUS FUMIGATUS |
Cellular location | Cytoplasm: Q9UVX3 |
Total number of polymer chains | 1 |
Total formula weight | 48913.05 |
Authors | Robinson, D.A.,Fang, W.,Raimi, O.G.,Blair, D.E.,Harrison, J.,Ruda, G.F.,Lockhart, D.E.A.,Torrie, L.S.,Wyatt, P.G.,Gilbert, I.H.,Van Aalten, D.M.F. (deposition date: 2013-10-09, release date: 2014-09-17, Last modification date: 2023-12-20) |
Primary citation | Fang, W.,Robinson, D.A.,Raimi, O.G.,Blair, D.E.,Harrison, J.R.,Lockhart, D.E.A.,Torrie, L.S.,Ruda, G.F.,Wyatt, P.G.,Gilbert, I.H.,Van Aalten, D.M.F. N-Myristoyltransferase is a Cell Wall Target in Aspergillus Fumigatus. Acs Chem.Biol., 10:1425-, 2015 Cited by PubMed: 25706802DOI: 10.1021/CB5008647 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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