4C8T
Xenopus ZNRF3 ectodomain crystal form I
Summary for 4C8T
Entry DOI | 10.2210/pdb4c8t/pdb |
Related | 4C84 4C85 4C86 4C8A 4C8C 4C8F 4C8P 4C8U 4C8V 4C8W 4C99 4C9A 4C9E 4C9R 4C9U 4C9V |
Descriptor | E3 UBIQUITIN-PROTEIN LIGASE ZNRF3 (2 entities in total) |
Functional Keywords | ligase, wnt, rnf43, lgr4, lgr5, lgr6, rspo, r-spondin, r-spo, rspo1, rspo2, rspo3, rspo4, receptor, membrane, signalling |
Biological source | XENOPUS (SILURANA) TROPICALIS (WESTERN CLAWED FROG) |
Cellular location | Cell membrane; Single-pass type I membrane protein (By similarity): Q08D68 |
Total number of polymer chains | 2 |
Total formula weight | 40988.03 |
Authors | Zebisch, M.,Jones, E.Y. (deposition date: 2013-10-01, release date: 2013-11-20, Last modification date: 2013-11-27) |
Primary citation | Zebisch, M.,Xu, Y.,Krastev, C.,Macdonald, B.T.,Chen, M.,Gilbert, R.J.C.,He, X.,Jones, E.Y. Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin. Nat.Commun., 4:2787-, 2013 Cited by PubMed: 24225776DOI: 10.1038/NCOMMS3787 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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