4C55

Crystal structure of serum-derived human IgG4 Fc

4C55 の概要

• エントリーDOI: 10.2210/pdb4c55/pdb
• 関連するPDBエントリー: 4C54
• 分子名称: IG GAMMA-4 CHAIN C REGION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: immune system, igg, antibody, immunoglobulin, igg1
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Secreted: P01861
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52966.99

構造登録者

Davies, A.M.,Rispens, T.,Ooijevaar-deHeer, P.,Gould, H.J.,Jefferis, R.,Aalberse, R.C.,Sutton, B.J. (登録日: 2013-09-10, 公開日: 2013-11-13, 最終更新日: 2023-12-20)

• 主引用文献: Davies, A.M.,Rispens, T.,Ooijevaar-Deheer, P.,Gould, H.J.,Jefferis, R.,Aalberse, R.C.,Sutton, B.J.; Structural Determinants of Unique Properties of Human Igg4-Fc; J.Mol.Biol., 426:630-, 2014; PubMed: 24211234; DOI: 10.1016/J.JMB.2013.10.039

実験手法

X-RAY DIFFRACTION (2.35 Å)