4C54

Crystal structure of recombinant human IgG4 Fc

Summary for 4C54

• Entry DOI: 10.2210/pdb4c54/pdb
• Related: 4C55
• Descriptor: IG GAMMA-4 CHAIN C REGION, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total)
• Functional Keywords: immune system, immunoglobulin, igg1
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 52372.41

Authors

Davies, A.M.,Rispens, T.,Ooijevaar-deHeer, P.,Gould, H.J.,Jefferis, R.,Aalberse, R.C.,Sutton, B.J. (deposition date: 2013-09-10, release date: 2013-11-13, Last modification date: 2023-12-20)

• Primary citation: Davies, A.M.,Rispens, T.,Ooijevaar-Deheer, P.,Gould, H.J.,Jefferis, R.,Aalberse, R.C.,Sutton, B.J.; Structural Determinants of Unique Properties of Human Igg4-Fc; J.Mol.Biol., 426:630-, 2014; PubMed: 24211234; DOI: 10.1016/J.JMB.2013.10.039

Experimental method

X-RAY DIFFRACTION (1.9 Å)